欧路词典
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  1. n. 对立〔对抗〕 者, 对手, 敌手
  2. <解>对抗肌
  3. <药>对抗药
形容词: antagonistic
副 词: antagonistically
n.
n.
联想词
villain坏人,恶棍;protagonist主角;villainous邪恶的;agonist收缩筋;villains恶棍;nemesis报应;antagonistic敌对的;character个性;heroine女英雄;inhibitor抑制物;sidekick伙伴,插袋;

His antagonist in the debate was quicker than he.

在辩论中他的对手比他应快。

Astemizole is H1-receptor antagonist, which is used to treat allergic disorder such as uredo and allergic rhinitis etc.

阿司咪唑为H1受体拮抗剂,主要用于荨麻疹、过敏性鼻炎等变态应性疾病的治疗。

According to the ethylene diamine moiety in the structure of some calcium antagonists,we designed and synthesized 5 unreported phenoxybenzamine derivatives.

利用酚苄结构中氯乙胺基的活性,结合一些钙拮抗剂含乙二胺结构的特征,设计合成了5个酚苄衍生物。

Objective To study the effect of intracerebroventricular injection of norepinephrine (NE) and a receptor antagonist phentolamine on withdrawal syndrome in morphinistic rats.

目的观察侧室注射去甲肾上腺素(NE)及其α受体阻断剂酚妥拉对吗啡成瘾大鼠戒断症状的影响。

Abstract The effects of neurotransmitters and receptor antagonists on HFO in phrenic discharge were observed in 65 unanaesthetized, vagotomized, paralyzed rabbits.

摘要 于65只清醒麻痹、迷走神经切断的家兔,观察室内注射中枢递质和受体阻断剂对膈神经放电高频振荡频率的影响。

Randomized aldactone evaluation study (RALES) showed that adding aldosterone antagonist in the treatment of heart failure may decrease 30% mortality of all causes.

随机螺内酯评估研究表在心力衰竭治疗中加用醛甾酮拮抗药可使总死亡率降低30%。

Mr.Morales, a former grower of coca, the raw ingredient of cocaine, is both an antagonist and an active partner in American antidrug policy for the region.

种过古柯碱原料古柯的莫拉雷斯,既跟美国在该区的毒政策,也是积极参与的夥伴。

:以上例句、词性分类均由互联网资源自动生成,部分未经过人工审核,其表达内容亦不代表本软件的观点;若发现问题,欢迎向我们指正。

显示所有包含 antagonist 的英语例句

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hypotrematic, Hypotricha, Hypotrichiales, Hypotrichida, hypotrichosis, hypotrichous, hypo-triploid, hypotrochanteric, hypotrochoid, hypotrophy,

相似单词


Antaen, Antaeus, antafossa, antagonise, antagonism, antagonist, antagonistic, antagonistical, antagonistically, antagonisticsubstance,
  1. n. 对立〔对抗〕 者, 对手, 敌手
  2. <解>对抗肌
  3. <药>对抗药
形容词: antagonistic
副 词: antagonistically
近义词
n.
反义词
n.
联想词
villain坏人,恶棍;protagonist主角;villainous邪恶的;agonist收缩筋;villains恶棍;nemesis报应;antagonistic敌对的;character个性;heroine女英雄;inhibitor抑制物;sidekick伙伴,插袋;

His antagonist in the debate was quicker than he.

在辩论中他的对手比他反应快。

Astemizole is H1-receptor antagonist, which is used to treat allergic disorder such as uredo and allergic rhinitis etc.

阿司咪唑为H1抗剂,主要用于荨麻疹、过敏性鼻炎等变态反应性疾病的治疗。

According to the ethylene diamine moiety in the structure of some calcium antagonists,we designed and synthesized 5 unreported phenoxybenzamine derivatives.

利用酚苄结构中氯乙胺基的活性,结一些钙抗剂含乙二胺结构的特征,设计5个酚苄衍生物。

Objective To study the effect of intracerebroventricular injection of norepinephrine (NE) and a receptor antagonist phentolamine on withdrawal syndrome in morphinistic rats.

目的观察侧脑室注射去甲肾上腺素(NE)及其α阻断剂酚妥拉对吗啡瘾大鼠戒断症状的影响。

Abstract The effects of neurotransmitters and receptor antagonists on HFO in phrenic discharge were observed in 65 unanaesthetized, vagotomized, paralyzed rabbits.

摘要 于65只清醒麻痹、迷走神经切断的家兔,观察第四脑室内注射中枢递质和阻断剂对膈神经放电高频振荡频率的影响。

Randomized aldactone evaluation study (RALES) showed that adding aldosterone antagonist in the treatment of heart failure may decrease 30% mortality of all causes.

随机螺内酯评估研究表在心力衰竭治疗中加用醛甾酮抗药可使总死亡率降低30%。

Mr.Morales, a former grower of coca, the raw ingredient of cocaine, is both an antagonist and an active partner in American antidrug policy for the region.

种过古柯碱原料古柯的莫拉雷斯,既跟美国在该区的反毒政策唱反调,也是积极参与的夥伴。

:以上例句、词性分类均由互联网资源自动生,部分未经过人工审核,其表达内容亦不代表本软件的观点;若发现问题,欢迎向我们指正。

显示所有包含 antagonist 的英语例句

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hypovarianism, hypovenosity, hypoventilation, hypovigilance, hypovitaminosis, hypovolaemia, hypovolemia, hypovolemic shock, hypovolia, hypoxaemia,

相似单词


Antaen, Antaeus, antafossa, antagonise, antagonism, antagonist, antagonistic, antagonistical, antagonistically, antagonisticsubstance,
  1. n. 立〔, 手, 敌手
  2. <解>
  3. <药>
形容词: antagonistic
副 词: antagonistically
近义词
n.
反义词
n.
联想词
villain坏人,恶棍;protagonist主角;villainous邪恶的;agonist收缩筋;villains恶棍;nemesis报应;antagonistic的;character个性;heroine女英雄;inhibitor抑制物;sidekick伙伴,插袋;

His antagonist in the debate was quicker than he.

在辩论中他的比他反应快。

Astemizole is H1-receptor antagonist, which is used to treat allergic disorder such as uredo and allergic rhinitis etc.

阿司咪唑为H1受体,主要用于荨麻疹、过敏性鼻炎等变态反应性疾病的治疗。

According to the ethylene diamine moiety in the structure of some calcium antagonists,we designed and synthesized 5 unreported phenoxybenzamine derivatives.

利用酚苄结构中氯乙胺基的活性,结合一些钙拮剂含乙二胺结构的特征,设计合成了5个酚苄衍生物。

Objective To study the effect of intracerebroventricular injection of norepinephrine (NE) and a receptor antagonist phentolamine on withdrawal syndrome in morphinistic rats.

目的观察侧脑室注射去甲肾上腺素(NE)及其α受体阻断剂酚妥拉吗啡成瘾大鼠戒断症状的影响。

Abstract The effects of neurotransmitters and receptor antagonists on HFO in phrenic discharge were observed in 65 unanaesthetized, vagotomized, paralyzed rabbits.

摘要 于65只清醒麻痹、迷走切断的家兔,观察第四脑室内注射中枢递质和受体阻断剂放电高频振荡频率的影响。

Randomized aldactone evaluation study (RALES) showed that adding aldosterone antagonist in the treatment of heart failure may decrease 30% mortality of all causes.

随机螺内酯评估研究表在心力衰竭治疗中加用醛甾酮拮药可使总死亡率降低30%。

Mr.Morales, a former grower of coca, the raw ingredient of cocaine, is both an antagonist and an active partner in American antidrug policy for the region.

种过古柯碱原料古柯的莫拉雷斯,既跟美国在该区的反毒政策唱反调,也是积极参与的夥伴。

:以上例句、词性分类均由互联网资源自动生成,部分未过人工审核,其表达内容亦不代表本软件的观点;若发现问题,欢迎向我们指正。

显示所有包含 antagonist 的英语例句

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hypozygal, hyppish, hypsarrhythmia, HYPSES, hypsibrachycephalic, hypsibrachycephalism, hypsicephalic, hypsicephalous, hypsicephaly, hypsiconch,

相似单词


Antaen, Antaeus, antafossa, antagonise, antagonism, antagonist, antagonistic, antagonistical, antagonistically, antagonisticsubstance,
  1. n. 对立〔对抗〕 者, 对手, 敌手
  2. <解>对抗肌
  3. <药>对抗药
形容词: antagonistic
副 词: antagonistically
近义词
n.
反义词
n.
联想词
villain坏人,恶棍;protagonist主角;villainous邪恶的;agonist收缩筋;villains恶棍;nemesis报应;antagonistic敌对的;character个性;heroine女英雄;inhibitor抑制物;sidekick伙伴,插袋;

His antagonist in the debate was quicker than he.

在辩论中他的对手比他反应快。

Astemizole is H1-receptor antagonist, which is used to treat allergic disorder such as uredo and allergic rhinitis etc.

阿司咪唑为H1受体拮抗剂,主要用于荨麻疹、过敏性鼻炎等变态反应性疾病的

According to the ethylene diamine moiety in the structure of some calcium antagonists,we designed and synthesized 5 unreported phenoxybenzamine derivatives.

用酚苄结构中基的活性,结合一些钙拮抗剂含结构的特征,设计合成了5个酚苄衍生物。

Objective To study the effect of intracerebroventricular injection of norepinephrine (NE) and a receptor antagonist phentolamine on withdrawal syndrome in morphinistic rats.

目的观察侧脑室注射去甲肾上腺素(NE)及其α受体阻断剂酚妥拉对吗啡成瘾大鼠戒断症状的影响。

Abstract The effects of neurotransmitters and receptor antagonists on HFO in phrenic discharge were observed in 65 unanaesthetized, vagotomized, paralyzed rabbits.

摘要 于65只清醒麻痹、迷走神经切断的家兔,观察第四脑室内注射中枢递质和受体阻断剂对膈神经放电高频振荡频率的影响。

Randomized aldactone evaluation study (RALES) showed that adding aldosterone antagonist in the treatment of heart failure may decrease 30% mortality of all causes.

随机螺内酯评估研究表在心力衰竭中加用醛甾酮拮抗药可使总死亡率降低30%。

Mr.Morales, a former grower of coca, the raw ingredient of cocaine, is both an antagonist and an active partner in American antidrug policy for the region.

种过古柯碱原料古柯的莫拉雷斯,既跟美国在该区的反毒政策唱反调,也是积极参与的夥伴。

:以上例句、词性分类均由互联网资源自动生成,部分未经过人工审核,其表达内容亦不代表本软件的观点;若发现问题,欢迎向我们指正。

显示所有包含 antagonist 的英语例句

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hypsogram, hypsographic, hypsography, hypsoisotherm, hypsokinesis, hypsometer, hypsometric, hypsometrical, hypsometrically, hypsometry,

相似单词


Antaen, Antaeus, antafossa, antagonise, antagonism, antagonist, antagonistic, antagonistical, antagonistically, antagonisticsubstance,
  1. n. 对立〔对抗〕 者, 对手, 敌手
  2. <解>对抗肌
  3. <药>对抗药
形容词: antagonistic
副 词: antagonistically
近义词
n.
反义词
n.
联想词
villain坏人,恶棍;protagonist主角;villainous邪恶;agonist收缩筋;villains恶棍;nemesis报应;antagonistic敌对;character个性;heroine女英雄;inhibitor抑制物;sidekick伙伴,插袋;

His antagonist in the debate was quicker than he.

在辩论对手反应快。

Astemizole is H1-receptor antagonist, which is used to treat allergic disorder such as uredo and allergic rhinitis etc.

阿司咪唑为H1受体拮抗剂,主要用于荨麻疹、过敏性鼻炎等变态反应性疾病治疗。

According to the ethylene diamine moiety in the structure of some calcium antagonists,we designed and synthesized 5 unreported phenoxybenzamine derivatives.

利用酚苄结构氯乙胺基活性,结合一些钙拮抗剂含乙二胺结构特征,设计合成了5个酚苄衍生物。

Objective To study the effect of intracerebroventricular injection of norepinephrine (NE) and a receptor antagonist phentolamine on withdrawal syndrome in morphinistic rats.

观察侧射去甲肾上腺素(NE)及其α受体阻断剂酚妥拉对吗啡成瘾大鼠戒断症状影响。

Abstract The effects of neurotransmitters and receptor antagonists on HFO in phrenic discharge were observed in 65 unanaesthetized, vagotomized, paralyzed rabbits.

摘要 于65只清醒麻痹、迷走神经切断家兔,观察第四枢递质和受体阻断剂对膈神经放电高频振荡频率影响。

Randomized aldactone evaluation study (RALES) showed that adding aldosterone antagonist in the treatment of heart failure may decrease 30% mortality of all causes.

随机螺内酯评估研究表在心力衰竭治疗加用醛甾酮拮抗药可使总死亡率降低30%。

Mr.Morales, a former grower of coca, the raw ingredient of cocaine, is both an antagonist and an active partner in American antidrug policy for the region.

种过古柯碱原料古柯莫拉雷斯,既跟美国在该区反毒政策唱反调,也是积极参与夥伴。

:以上例句、词性分类均由互联网资源自动生成,部分未经过人工审核,其表达内容亦不代表本软件观点;若发现问题,欢迎向我们指正。

显示所有包含 antagonist 的英语例句

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hypurgia, hyqnagoguo, hyraces, hyraceum, hyracid, hyraciform, hyracodon, hyracodont, hyracoid, Hyracoidea,

相似单词


Antaen, Antaeus, antafossa, antagonise, antagonism, antagonist, antagonistic, antagonistical, antagonistically, antagonisticsubstance,

用户正在搜索


hysterocarcinoma, hysterocatalepsy, hysterocataphraxis, hysterocele, hysterocervicetomy, hysterocervicotomy, hysterochroic, hysterocleisis, hysterocolpectomy, hysterocolposcope,

相似单词


Antaen, Antaeus, antafossa, antagonise, antagonism, antagonist, antagonistic, antagonistical, antagonistically, antagonisticsubstance,
  1. n. 对立〔对抗〕 者, 对手, 敌手
  2. <解>对抗肌
  3. <药>对抗药
形容词: antagonistic
副 词: antagonistically
近义词
n.
反义词
n.
联想词
villain坏人,恶棍;protagonist主角;villainous邪恶的;agonist收缩筋;villains恶棍;nemesis报应;antagonistic敌对的;character个性;heroine女英雄;inhibitor抑制物;sidekick伙伴,插袋;

His antagonist in the debate was quicker than he.

他的对手比他反应快。

Astemizole is H1-receptor antagonist, which is used to treat allergic disorder such as uredo and allergic rhinitis etc.

阿司咪唑为H1受体拮抗剂,主要用于荨麻疹、过敏性鼻炎等变态反应性疾病的治疗。

According to the ethylene diamine moiety in the structure of some calcium antagonists,we designed and synthesized 5 unreported phenoxybenzamine derivatives.

利用酚苄结构氯乙胺基的活性,结合一些钙拮抗剂含乙二胺结构的特征,设计合成了5个酚苄衍生物。

Objective To study the effect of intracerebroventricular injection of norepinephrine (NE) and a receptor antagonist phentolamine on withdrawal syndrome in morphinistic rats.

目的观察侧脑室甲肾上腺素(NE)及其α受体阻断剂酚妥拉对吗啡成瘾大鼠戒断症状的影响。

Abstract The effects of neurotransmitters and receptor antagonists on HFO in phrenic discharge were observed in 65 unanaesthetized, vagotomized, paralyzed rabbits.

摘要 于65只清醒麻痹、迷走神经切断的家兔,观察第四脑室内枢递质和受体阻断剂对膈神经放电高频振荡频率的影响。

Randomized aldactone evaluation study (RALES) showed that adding aldosterone antagonist in the treatment of heart failure may decrease 30% mortality of all causes.

随机螺内酯评估研究表在心力衰竭治疗加用醛甾酮拮抗药可使总死亡率降低30%。

Mr.Morales, a former grower of coca, the raw ingredient of cocaine, is both an antagonist and an active partner in American antidrug policy for the region.

种过古柯碱原料古柯的莫拉雷斯,既跟美国在该区的反毒政策唱反调,也是积极参与的夥伴。

:以上例句、词性分类均由互联网资源自动生成,部分未经过人工审核,其表达内容亦不代表本软件的观点;若发现问题,欢迎向我们指正。

显示所有包含 antagonist 的英语例句

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hysterofrenic, hysterofundusectomy, hysterogastrorrhaphy, hysterogenetic, hysterogenic, hysterogram, hysterograph, hysterography, hysteroid, hysteroidal,

相似单词


Antaen, Antaeus, antafossa, antagonise, antagonism, antagonist, antagonistic, antagonistical, antagonistically, antagonisticsubstance,
  1. n. 对立〔对抗〕 者, 对手, 敌手
  2. <解>对抗肌
  3. <药>对抗药
形容词: antagonistic
副 词: antagonistically
近义词
n.
反义词
n.
联想词
villain坏人,恶棍;protagonist主角;villainous邪恶的;agonist收缩筋;villains恶棍;nemesis报应;antagonistic敌对的;character个性;heroine女英;inhibitor物;sidekick伙伴,插袋;

His antagonist in the debate was quicker than he.

在辩论中他的对手比他反应快。

Astemizole is H1-receptor antagonist, which is used to treat allergic disorder such as uredo and allergic rhinitis etc.

阿司咪唑为H1受体拮抗,主要用于荨麻疹、过敏性鼻炎等变态反应性疾病的治疗。

According to the ethylene diamine moiety in the structure of some calcium antagonists,we designed and synthesized 5 unreported phenoxybenzamine derivatives.

利用结构中氯乙胺基的活性,结合一些钙拮抗含乙二胺结构的特征,设计合成了5个衍生物。

Objective To study the effect of intracerebroventricular injection of norepinephrine (NE) and a receptor antagonist phentolamine on withdrawal syndrome in morphinistic rats.

目的观察侧脑室注射去甲肾上腺素(NE)及其α受体阻断对吗啡成瘾大鼠戒断症状的影响。

Abstract The effects of neurotransmitters and receptor antagonists on HFO in phrenic discharge were observed in 65 unanaesthetized, vagotomized, paralyzed rabbits.

摘要 于65只清醒麻痹、迷走神经切断的家兔,观察第四脑室内注射中枢递质和受体阻断对膈神经放电高频振荡频率的影响。

Randomized aldactone evaluation study (RALES) showed that adding aldosterone antagonist in the treatment of heart failure may decrease 30% mortality of all causes.

随机螺内酯评估研究表在心力衰竭治疗中加用醛甾酮拮抗药可使总死亡率降低30%。

Mr.Morales, a former grower of coca, the raw ingredient of cocaine, is both an antagonist and an active partner in American antidrug policy for the region.

种过古柯碱原料古柯的莫拉雷斯,既跟美国在该区的反毒政策唱反调,也是积极参与的夥伴。

:以上例句、词性分类均由互联网资源自动生成,部分未经过人工审核,其表达内容亦不代表本软件的观点;若发现问题,欢迎向我们指正。

显示所有包含 antagonist 的英语例句

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hysterometry, hysteromucography, hysteromyoma, hysteromyomectomia, hysteromyomectomy, hysteromyotomy, hysteronarcolepsy, hysteroneurasthenia, hysteroneurosis, hystero-oophorectomy,

相似单词


Antaen, Antaeus, antafossa, antagonise, antagonism, antagonist, antagonistic, antagonistical, antagonistically, antagonisticsubstance,
  1. n. 对立〔对抗〕 者, 对手, 敌手
  2. <解>对抗肌
  3. <药>对抗药
形容词: antagonistic
副 词: antagonistically
近义词
n.
反义词
n.
联想词
villain坏人,恶棍;protagonist主角;villainous邪恶的;agonist收缩筋;villains恶棍;nemesis报应;antagonistic敌对的;character个性;heroine女英;inhibitor制物;sidekick伙伴,插袋;

His antagonist in the debate was quicker than he.

在辩论中他的对手比他反应快。

Astemizole is H1-receptor antagonist, which is used to treat allergic disorder such as uredo and allergic rhinitis etc.

阿司咪唑为H1受体拮抗剂,主要用于荨麻疹、过敏性鼻炎等变态反应性疾病的治疗。

According to the ethylene diamine moiety in the structure of some calcium antagonists,we designed and synthesized 5 unreported phenoxybenzamine derivatives.

利用结构中氯乙胺基的活性,结合一些钙拮抗剂含乙二胺结构的特征,设计合成了5个衍生物。

Objective To study the effect of intracerebroventricular injection of norepinephrine (NE) and a receptor antagonist phentolamine on withdrawal syndrome in morphinistic rats.

目的观察侧脑室注射去甲肾上腺素(NE)及其α受体阻断剂对吗啡成瘾大鼠戒断症状的影响。

Abstract The effects of neurotransmitters and receptor antagonists on HFO in phrenic discharge were observed in 65 unanaesthetized, vagotomized, paralyzed rabbits.

摘要 于65只清醒麻痹、迷走神经切断的家兔,观察第四脑室内注射中枢递质和受体阻断剂对膈神经放电高频振荡频率的影响。

Randomized aldactone evaluation study (RALES) showed that adding aldosterone antagonist in the treatment of heart failure may decrease 30% mortality of all causes.

随机螺内酯评估研究表在心力衰竭治疗中加用醛甾酮拮抗药可使总死亡率降低30%。

Mr.Morales, a former grower of coca, the raw ingredient of cocaine, is both an antagonist and an active partner in American antidrug policy for the region.

种过古柯碱原料古柯的莫雷斯,既跟美国在该区的反毒政策唱反调,也是积极参与的夥伴。

:以上例句、词性分类均由互联网资源自动生成,部分未经过人工审核,其表达内容亦不代表本软件的观点;若发现问题,欢迎向我们指正。

显示所有包含 antagonist 的英语例句

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hysteroptosia, hysteroptosis, hysterorrhaphy, hysterorrhexis, hysterosalpingectomy, hysterosalpingography, hysterosalpingo-oophorectomy, hysterosalpingostomy, hysteroscope, hysteroscopy,

相似单词


Antaen, Antaeus, antafossa, antagonise, antagonism, antagonist, antagonistic, antagonistical, antagonistically, antagonisticsubstance,
  1. n. 对立〔对抗〕 者, 对手, 敌手
  2. <解>对抗肌
  3. <药>对抗药
形容词: antagonistic
副 词: antagonistically
近义词
n.
反义词
n.
联想词
villain坏人,恶棍;protagonist主角;villainous邪恶的;agonist收缩筋;villains恶棍;nemesis报应;antagonistic敌对的;character个性;heroine女英雄;inhibitor抑制物;sidekick伙伴,插袋;

His antagonist in the debate was quicker than he.

在辩论中他的对手比他反应快。

Astemizole is H1-receptor antagonist, which is used to treat allergic disorder such as uredo and allergic rhinitis etc.

唑为H1受体拮抗剂,主要用于荨麻疹、过敏性鼻炎等变态反应性疾病的治疗。

According to the ethylene diamine moiety in the structure of some calcium antagonists,we designed and synthesized 5 unreported phenoxybenzamine derivatives.

利用酚结构中氯乙胺基的活性,结合一些钙拮抗剂含乙二胺结构的特征,设计合成了5个酚生物。

Objective To study the effect of intracerebroventricular injection of norepinephrine (NE) and a receptor antagonist phentolamine on withdrawal syndrome in morphinistic rats.

目的观察侧脑室注射去甲肾上腺素(NE)及其α受体阻断剂酚妥拉对吗啡成瘾大鼠戒断症状的影响。

Abstract The effects of neurotransmitters and receptor antagonists on HFO in phrenic discharge were observed in 65 unanaesthetized, vagotomized, paralyzed rabbits.

摘要 于65只清醒麻痹、迷走神经切断的家兔,观察第四脑室内注射中枢递质和受体阻断剂对膈神经放电高频振荡频率的影响。

Randomized aldactone evaluation study (RALES) showed that adding aldosterone antagonist in the treatment of heart failure may decrease 30% mortality of all causes.

随机螺内酯评估研究表在心力衰竭治疗中加用醛甾酮拮抗药可使总死亡率降低30%。

Mr.Morales, a former grower of coca, the raw ingredient of cocaine, is both an antagonist and an active partner in American antidrug policy for the region.

种过古柯碱原料古柯的莫拉雷斯,既跟美国在该区的反毒政策唱反调,也是积极参与的夥伴。

:以上例句、词性分类均由互联网资源自动生成,部分未经过人工审核,其表达内容亦不代表本软件的观点;若发现问题,欢迎向我们指正。

显示所有包含 antagonist 的英语例句

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hysterothecium, hysterothermometry, hysterotokotomy, hysterotome, hysterotomotokia, hysterotomy, hysterotonics, hysterotrachelectasia, hysterotrachelectomy, hysterotracheloplasty,

相似单词


Antaen, Antaeus, antafossa, antagonise, antagonism, antagonist, antagonistic, antagonistical, antagonistically, antagonisticsubstance,