However by 8 week IUGR rats developed hyper-insulinemia and high IRI.

胰岛素耐量实验显示IUGR子鼠对外源性胰岛素反应迟钝。

Therefore, an agent that has dual action (insulin secretagougue and sensitisation) is preferred for T2DM.

所以，有此双重作用（胰岛素促泌及增敏）的药适用于T2DM。

In addition, there was breed difference of synergistic effect of glucose of insulin on lipogenesis.

同时，胰岛素和葡萄糖对脂肪生的协同效应存品种差异。

It has since been demonstrated that topiramate can act both as an insulin secretagogue and sensitiser in T2DM animal models.

这说明T2DM模型中，托吡酯同时有胰岛素促泌剂和胰岛素增敏剂作用。

Fructose was mainly used in metabolism in vivo,heat production,endogeny glucogenesis and insulin,platelet,microelement,and promoting cell caryocinesia or cytoprotection.

果糖主要用于体内代谢和产热、内源葡萄糖生与胰岛素、血小板、体内微量元素及促进胞有丝分裂和胞保护。

It is suggested that lumbosacral agenesis, a severe congenital defect, might be one of the anomalies of diabetic embryopathy.

此病例显示腰荐椎发育不全可能是母亲糖尿病所导致胚胎病变的一种，且无论有无接受胰岛素治疗，此先天畸仍可能。

So both cross-sectionally and prospectively researches have focused on the role of insulin resistance in the worsening of glucose tolerance.

此，横断面研究和前瞻性研究的研究焦点都于胰岛素抵抗糖耐量减低中的作用。

The key to treatment is to find and cope with shock, dehydration and hyperosmolality, especially to control blood sugar level with insulin.

救治的关键是及早发现并尽快抢救休克、纠正脱水、纠正高渗状态，注意控制血糖是治疗关键，静滴胰岛素极其有效。

Moreover presence of insulin resistance and diabetes are risk factors for fibrosis progression and nonresponse to antiviral therapy in chronic hepatitis C (CHC).

此外，胰岛素抵抗和糖尿病是慢性丙型肝炎（CHC）中纤维化进展以及对抗病毒治疗无应答的危险素。

Conclusion: There is insulin resistance in patients with cerebral lacunal infarction.Cerebral insulin resistance may be one of its risk factors for cerebral lacunal infarction.

腔隙性脑梗塞患者存胰岛素抵抗，胰岛素抵抗可能是腔隙性脑梗塞的危险素之一。

Retinaldehyde (Rald), a metabolite of itamin A, increases the generation of adipose tissue and decreases insulin sensitiity, work conducted in a Harard Uniersity laboratory shows.

哈佛大学研究结果表明，维生素A的代谢产视黄醛可以增加脂肪组织生，降低胰岛素敏感性。

Abstract: Objective To evaluate the clinical efficacy of dimethyldiguanide and Gliclazide capsule in treatment of type 2 diabetic insulin resistance (IR) and fat metabolism disorder.

目的观察比较二甲双胍与格列齐特对2型糖尿病胰岛素抵抗(IR)及脂代谢紊乱的疗效。

A report recently published in the American Journal of Epidemiology suggested that smoking increased the risk of developing non-insulin-dependent diabetes mellitus (NIDDM) by more than three times.

美国《流行病学杂志》最近发表的一份报告表明，吸烟使人们患非胰岛素依赖型糖尿病的危险增加了3倍多。

In conclusion, LBP possess the action of lowing blood glucose, improving morphogeny and function of pancreatic islet B cells and increasing the secretion of insulin in NIDDM mice.

枸杞多糖可以改善Ⅱ型糖尿病小鼠胰岛胞态和功能并促进胰岛素的分泌，有良好的降血糖作用。

Our results provide evidence that small islets are superior to large islets with regard to in vitro insulin secretion and show a higher survival rate during both normoxic and hypoxic culture.

结果证明，不论是含氧量正常还是低氧培养条件下，小胰岛体外胰岛素分泌方面由于大胰岛，并显示出相对较高的存活率。

However by 8 week IUGR rats developed hyper-insulinemia and high IRI.

胰耐量实验显示IUGR子鼠对外源性胰反应迟钝。

Therefore, an agent that has dual action (insulin secretagougue and sensitisation) is preferred for T2DM.

所以，有此双重作用（胰促泌及增敏）的药物适用于T2DM。

In addition, there was breed difference of synergistic effect of glucose of insulin on lipogenesis.

同时，胰葡萄糖对脂肪生成的协同效应存在品种差异。

It has since been demonstrated that topiramate can act both as an insulin secretagogue and sensitiser in T2DM animal models.

这说明在T2DM动物模型中，托吡酯同时有胰促泌剂胰增敏剂作用。

Fructose was mainly used in metabolism in vivo,heat production,endogeny glucogenesis and insulin,platelet,microelement,and promoting cell caryocinesia or cytoprotection.

果糖主要用于体内代谢产热、内源葡萄糖生成与胰、血小板、体内微量元及促进胞有丝分裂胞保护。

It is suggested that lumbosacral agenesis, a severe congenital defect, might be one of the anomalies of diabetic embryopathy.

此病例显示腰荐椎发育不全可能是母亲糖尿病所导致胚胎病变的一种，且无论有无接受胰治疗，此先天畸形仍可能形成。

So both cross-sectionally and prospectively researches have focused on the role of insulin resistance in the worsening of glucose tolerance.

因此，横断面研究前瞻性研究的研究焦点都在于胰在糖耐量减低中的作用。

The key to treatment is to find and cope with shock, dehydration and hyperosmolality, especially to control blood sugar level with insulin.

救治的关键是及早发现并尽快抢救休克、纠正脱水、纠正高渗状态，注意控制血糖是治疗关键，静滴胰极其有效。

Moreover presence of insulin resistance and diabetes are risk factors for fibrosis progression and nonresponse to antiviral therapy in chronic hepatitis C (CHC).

此外，胰糖尿病是慢性丙型肝炎（CHC）中纤维化进展以及对病毒治疗无应答的危险因。

Conclusion: There is insulin resistance in patients with cerebral lacunal infarction.Cerebral insulin resistance may be one of its risk factors for cerebral lacunal infarction.

腔隙性脑梗塞患者存在胰，胰可能是腔隙性脑梗塞的危险因之一。

Retinaldehyde (Rald), a metabolite of itamin A, increases the generation of adipose tissue and decreases insulin sensitiity, work conducted in a Harard Uniersity laboratory shows.

哈佛大学研究结果表明，维生A的代谢产物视黄醛可以增加脂肪组织生成，降低胰敏感性。

Abstract: Objective To evaluate the clinical efficacy of dimethyldiguanide and Gliclazide capsule in treatment of type 2 diabetic insulin resistance (IR) and fat metabolism disorder.

目的观察比较二甲双胍与格列齐特对2型糖尿病胰(IR)及脂代谢紊乱的疗效。

A report recently published in the American Journal of Epidemiology suggested that smoking increased the risk of developing non-insulin-dependent diabetes mellitus (NIDDM) by more than three times.

美国《流行病学杂志》最近发表的一份报告表明，吸烟使人们患非胰依赖型糖尿病的危险增加了3倍多。

In conclusion, LBP possess the action of lowing blood glucose, improving morphogeny and function of pancreatic islet B cells and increasing the secretion of insulin in NIDDM mice.

枸杞多糖可以改善Ⅱ型糖尿病小鼠胰胞形态功能并促进胰的分泌，有良好的降血糖作用。

Our results provide evidence that small islets are superior to large islets with regard to in vitro insulin secretion and show a higher survival rate during both normoxic and hypoxic culture.

结果证明，不论是含氧量正常还是在低氧培养条件下，小胰在体外胰分泌方面由于大胰，并显示出相对较高的存活率。

However by 8 week IUGR rats developed hyper-insulinemia and high IRI.

胰岛素耐量实验显示IUGR子鼠对外源性胰岛素反应迟钝。

Therefore, an agent that has dual action (insulin secretagougue and sensitisation) is preferred for T2DM.

所以，有此双重作用（胰岛素促泌及增敏）的药物适用于T2DM。

In addition, there was breed difference of synergistic effect of glucose of insulin on lipogenesis.

同时，胰岛素和葡萄糖对脂肪生成的协同效应存在品种差异。

It has since been demonstrated that topiramate can act both as an insulin secretagogue and sensitiser in T2DM animal models.

这说明在T2DM动物模型，酯同时有胰岛素促泌剂和胰岛素增敏剂作用。

Fructose was mainly used in metabolism in vivo,heat production,endogeny glucogenesis and insulin,platelet,microelement,and promoting cell caryocinesia or cytoprotection.

果糖主要用于体内代谢和产热、内源葡萄糖生成与胰岛素、血小板、体内微量元素及促进胞有丝分裂和胞保护。

It is suggested that lumbosacral agenesis, a severe congenital defect, might be one of the anomalies of diabetic embryopathy.

此病例显示腰荐椎发育不全可能是母亲糖尿病所导致胚胎病变的一种，且无论有无接受胰岛素治疗，此先天可能成。

So both cross-sectionally and prospectively researches have focused on the role of insulin resistance in the worsening of glucose tolerance.

因此，横断面研究和前瞻性研究的研究焦点都在于胰岛素抵抗在糖耐量减低的作用。

The key to treatment is to find and cope with shock, dehydration and hyperosmolality, especially to control blood sugar level with insulin.

救治的关键是及早发现并尽快抢救休克、纠正脱水、纠正高渗状态，注意控制血糖是治疗关键，静滴胰岛素极其有效。

Moreover presence of insulin resistance and diabetes are risk factors for fibrosis progression and nonresponse to antiviral therapy in chronic hepatitis C (CHC).

此外，胰岛素抵抗和糖尿病是慢性丙型肝炎（CHC）纤维化进展以及对抗病毒治疗无应答的危险因素。

Conclusion: There is insulin resistance in patients with cerebral lacunal infarction.Cerebral insulin resistance may be one of its risk factors for cerebral lacunal infarction.

腔隙性脑梗塞患者存在胰岛素抵抗，胰岛素抵抗可能是腔隙性脑梗塞的危险因素之一。

Retinaldehyde (Rald), a metabolite of itamin A, increases the generation of adipose tissue and decreases insulin sensitiity, work conducted in a Harard Uniersity laboratory shows.

哈佛大学研究结果表明，维生素A的代谢产物视黄醛可以增加脂肪组织生成，降低胰岛素敏感性。

Abstract: Objective To evaluate the clinical efficacy of dimethyldiguanide and Gliclazide capsule in treatment of type 2 diabetic insulin resistance (IR) and fat metabolism disorder.

目的观察比较二甲双胍与格列齐特对2型糖尿病胰岛素抵抗(IR)及脂代谢紊乱的疗效。

A report recently published in the American Journal of Epidemiology suggested that smoking increased the risk of developing non-insulin-dependent diabetes mellitus (NIDDM) by more than three times.

美国《流行病学杂志》最近发表的一份报告表明，吸烟使人们患非胰岛素依赖型糖尿病的危险增加了3倍多。

In conclusion, LBP possess the action of lowing blood glucose, improving morphogeny and function of pancreatic islet B cells and increasing the secretion of insulin in NIDDM mice.

枸杞多糖可以改善Ⅱ型糖尿病小鼠胰岛胞态和功能并促进胰岛素的分泌，有良好的降血糖作用。

Our results provide evidence that small islets are superior to large islets with regard to in vitro insulin secretion and show a higher survival rate during both normoxic and hypoxic culture.

结果证明，不论是含氧量正常还是在低氧培养条件下，小胰岛在体外胰岛素分泌方面由于大胰岛，并显示出相对较高的存活率。

However by 8 week IUGR rats developed hyper-insulinemia and high IRI.

胰岛实验显示IUGR子鼠对外源性胰岛反应迟钝。

Therefore, an agent that has dual action (insulin secretagougue and sensitisation) is preferred for T2DM.

所以，有此双重作用（胰岛促泌及增敏）的药物适用于T2DM。

In addition, there was breed difference of synergistic effect of glucose of insulin on lipogenesis.

同时，胰岛和葡萄对脂肪生成的协同效应存在品种差异。

It has since been demonstrated that topiramate can act both as an insulin secretagogue and sensitiser in T2DM animal models.

这说明在T2DM动物模型中，托吡酯同时有胰岛促泌剂和胰岛增敏剂作用。

Fructose was mainly used in metabolism in vivo,heat production,endogeny glucogenesis and insulin,platelet,microelement,and promoting cell caryocinesia or cytoprotection.

果主要用于体内代谢和产热、内源葡萄生成与胰岛、血小板、体内微元及促进胞有丝分裂和胞保护。

It is suggested that lumbosacral agenesis, a severe congenital defect, might be one of the anomalies of diabetic embryopathy.

此病例显示腰荐椎发育不全可能母亲尿病所导致胚胎病变的一种，且无论有无接受胰岛疗，此先天畸形仍可能形成。

So both cross-sectionally and prospectively researches have focused on the role of insulin resistance in the worsening of glucose tolerance.

因此，横断面研究和前瞻性研究的研究焦点都在于胰岛抵抗在减低中的作用。

The key to treatment is to find and cope with shock, dehydration and hyperosmolality, especially to control blood sugar level with insulin.

救的关键及早发现并尽快抢救休克、纠正脱水、纠正高渗状态，注意控制血疗关键，静滴胰岛极其有效。

Moreover presence of insulin resistance and diabetes are risk factors for fibrosis progression and nonresponse to antiviral therapy in chronic hepatitis C (CHC).

此外，胰岛抵抗和尿病慢性丙型肝炎（CHC）中纤维化进展以及对抗病毒疗无应答的危险因。

Conclusion: There is insulin resistance in patients with cerebral lacunal infarction.Cerebral insulin resistance may be one of its risk factors for cerebral lacunal infarction.

腔隙性脑梗塞患者存在胰岛抵抗，胰岛抵抗可能腔隙性脑梗塞的危险因之一。

Retinaldehyde (Rald), a metabolite of itamin A, increases the generation of adipose tissue and decreases insulin sensitiity, work conducted in a Harard Uniersity laboratory shows.

哈佛大学研究结果表明，维生A的代谢产物视黄醛可以增加脂肪组织生成，降低胰岛敏感性。

Abstract: Objective To evaluate the clinical efficacy of dimethyldiguanide and Gliclazide capsule in treatment of type 2 diabetic insulin resistance (IR) and fat metabolism disorder.

目的观察比较二甲双胍与格列齐特对2型尿病胰岛抵抗(IR)及脂代谢紊乱的疗效。

A report recently published in the American Journal of Epidemiology suggested that smoking increased the risk of developing non-insulin-dependent diabetes mellitus (NIDDM) by more than three times.

美国《流行病学杂志》最近发表的一份报告表明，吸烟使人们患非胰岛依赖型尿病的危险增加了3倍多。

In conclusion, LBP possess the action of lowing blood glucose, improving morphogeny and function of pancreatic islet B cells and increasing the secretion of insulin in NIDDM mice.

枸杞多可以改善Ⅱ型尿病小鼠胰岛胞形态和功能并促进胰岛的分泌，有良好的降血作用。

Our results provide evidence that small islets are superior to large islets with regard to in vitro insulin secretion and show a higher survival rate during both normoxic and hypoxic culture.

结果证明，不论含氧正常还在低氧培养条件下，小胰岛在体外胰岛分泌方面由于大胰岛，并显示出相对较高的存活率。

However by 8 week IUGR rats developed hyper-insulinemia and high IRI.

耐量实验显示IUGR子鼠对外源性反应迟钝。

Therefore, an agent that has dual action (insulin secretagougue and sensitisation) is preferred for T2DM.

所以，有此双重作用（促泌及增敏）的药物适用于T2DM。

In addition, there was breed difference of synergistic effect of glucose of insulin on lipogenesis.

同时，和葡萄糖对脂肪成的协同效应存在品种差异。

It has since been demonstrated that topiramate can act both as an insulin secretagogue and sensitiser in T2DM animal models.

这说明在T2DM动物模型中，托吡酯同时有促泌剂和增敏剂作用。

Fructose was mainly used in metabolism in vivo,heat production,endogeny glucogenesis and insulin,platelet,microelement,and promoting cell caryocinesia or cytoprotection.

果糖主要用于体内代谢和产热、内源葡萄糖成与、血小板、体内微量元及促进胞有丝分裂和胞保护。

It is suggested that lumbosacral agenesis, a severe congenital defect, might be one of the anomalies of diabetic embryopathy.

此病例显示腰荐椎发育不全可能是母亲糖尿病所导致胚胎病变的一种，且无论有无接受治疗，此先天畸形仍可能形成。

So both cross-sectionally and prospectively researches have focused on the role of insulin resistance in the worsening of glucose tolerance.

因此，横断面研究和前瞻性研究的研究焦点都在于抵抗在糖耐量减低中的作用。

The key to treatment is to find and cope with shock, dehydration and hyperosmolality, especially to control blood sugar level with insulin.

救治的关键是及早发现并尽快抢救休克、纠正脱水、纠正高渗状态，注意控制血糖是治疗关键，静滴极其有效。

Moreover presence of insulin resistance and diabetes are risk factors for fibrosis progression and nonresponse to antiviral therapy in chronic hepatitis C (CHC).

此外，抵抗和糖尿病是慢性丙型肝炎（CHC）中纤维化进展以及对抗病毒治疗无应答的危险因。

Conclusion: There is insulin resistance in patients with cerebral lacunal infarction.Cerebral insulin resistance may be one of its risk factors for cerebral lacunal infarction.

腔隙性脑梗塞患者存在抵抗，抵抗可能是腔隙性脑梗塞的危险因之一。

Retinaldehyde (Rald), a metabolite of itamin A, increases the generation of adipose tissue and decreases insulin sensitiity, work conducted in a Harard Uniersity laboratory shows.

哈佛大学研究结果表明，维A的代谢产物视黄醛可以增加脂肪组织成，降低敏感性。

Abstract: Objective To evaluate the clinical efficacy of dimethyldiguanide and Gliclazide capsule in treatment of type 2 diabetic insulin resistance (IR) and fat metabolism disorder.

目的观察比较二甲双胍与格列齐特对2型糖尿病抵抗(IR)及脂代谢紊乱的疗效。

A report recently published in the American Journal of Epidemiology suggested that smoking increased the risk of developing non-insulin-dependent diabetes mellitus (NIDDM) by more than three times.

美国《流行病学杂志》最近发表的一份报告表明，吸烟使人们患非依赖型糖尿病的危险增加了3倍多。

In conclusion, LBP possess the action of lowing blood glucose, improving morphogeny and function of pancreatic islet B cells and increasing the secretion of insulin in NIDDM mice.

枸杞多糖可以改善Ⅱ型糖尿病小鼠胞形态和功能并促进的分泌，有良好的降血糖作用。

Our results provide evidence that small islets are superior to large islets with regard to in vitro insulin secretion and show a higher survival rate during both normoxic and hypoxic culture.

结果证明，不论是含氧量正常还是在低氧培养条件下，小在体外分泌方面由于大，并显示出相对较高的存活率。

However by 8 week IUGR rats developed hyper-insulinemia and high IRI.

胰岛素耐量实验显示IUGR子鼠对外性胰岛素反应迟钝。

Therefore, an agent that has dual action (insulin secretagougue and sensitisation) is preferred for T2DM.

所以，有此双重作用（胰岛素促泌及增敏）的药物适用于T2DM。

In addition, there was breed difference of synergistic effect of glucose of insulin on lipogenesis.

同时，胰岛素和萄糖对脂肪生成的协同效应存在品种差异。

It has since been demonstrated that topiramate can act both as an insulin secretagogue and sensitiser in T2DM animal models.

这说明在T2DM动物模型中，托吡酯同时有胰岛素促泌剂和胰岛素增敏剂作用。

Fructose was mainly used in metabolism in vivo,heat production,endogeny glucogenesis and insulin,platelet,microelement,and promoting cell caryocinesia or cytoprotection.

果糖主要用于体代谢和产热、萄糖生成与胰岛素、血小板、体微量元素及促进胞有丝分裂和胞保护。

It is suggested that lumbosacral agenesis, a severe congenital defect, might be one of the anomalies of diabetic embryopathy.

此病例显示腰荐椎发育能是母亲糖尿病所导致胚胎病变的一种，且无论有无接受胰岛素治疗，此先天畸形仍能形成。

So both cross-sectionally and prospectively researches have focused on the role of insulin resistance in the worsening of glucose tolerance.

因此，横断面研究和前瞻性研究的研究焦点都在于胰岛素抵抗在糖耐量减低中的作用。

The key to treatment is to find and cope with shock, dehydration and hyperosmolality, especially to control blood sugar level with insulin.

救治的关键是及早发现并尽快抢救休克、纠正脱水、纠正高渗状态，注意控制血糖是治疗关键，静滴胰岛素极其有效。

Moreover presence of insulin resistance and diabetes are risk factors for fibrosis progression and nonresponse to antiviral therapy in chronic hepatitis C (CHC).

此外，胰岛素抵抗和糖尿病是慢性丙型肝炎（CHC）中纤维化进展以及对抗病毒治疗无应答的危险因素。

Conclusion: There is insulin resistance in patients with cerebral lacunal infarction.Cerebral insulin resistance may be one of its risk factors for cerebral lacunal infarction.

腔隙性脑梗塞患者存在胰岛素抵抗，胰岛素抵抗能是腔隙性脑梗塞的危险因素之一。

Retinaldehyde (Rald), a metabolite of itamin A, increases the generation of adipose tissue and decreases insulin sensitiity, work conducted in a Harard Uniersity laboratory shows.

哈佛大学研究结果表明，维生素A的代谢产物视黄醛以增加脂肪组织生成，降低胰岛素敏感性。

Abstract: Objective To evaluate the clinical efficacy of dimethyldiguanide and Gliclazide capsule in treatment of type 2 diabetic insulin resistance (IR) and fat metabolism disorder.

目的观察比较二甲双胍与格列齐特对2型糖尿病胰岛素抵抗(IR)及脂代谢紊乱的疗效。

A report recently published in the American Journal of Epidemiology suggested that smoking increased the risk of developing non-insulin-dependent diabetes mellitus (NIDDM) by more than three times.

美国《流行病学杂志》最近发表的一份报告表明，吸烟使人们患非胰岛素依赖型糖尿病的危险增加了3倍多。

In conclusion, LBP possess the action of lowing blood glucose, improving morphogeny and function of pancreatic islet B cells and increasing the secretion of insulin in NIDDM mice.

枸杞多糖以改善Ⅱ型糖尿病小鼠胰岛胞形态和功能并促进胰岛素的分泌，有良好的降血糖作用。

Our results provide evidence that small islets are superior to large islets with regard to in vitro insulin secretion and show a higher survival rate during both normoxic and hypoxic culture.

结果证明，论是含氧量正常还是在低氧培养条件下，小胰岛在体外胰岛素分泌方面由于大胰岛，并显示出相对较高的存活率。

However by 8 week IUGR rats developed hyper-insulinemia and high IRI.

素耐量实验显示IUGR子鼠对外源素反应迟钝。

Therefore, an agent that has dual action (insulin secretagougue and sensitisation) is preferred for T2DM.

所以，有此双重作用（素促泌及增敏）的药物适用于T2DM。

In addition, there was breed difference of synergistic effect of glucose of insulin on lipogenesis.

同时，素和葡萄糖对脂肪生成的协同效应存在品种差异。

It has since been demonstrated that topiramate can act both as an insulin secretagogue and sensitiser in T2DM animal models.

这说明在T2DM动物模型中，托吡酯同时有素促泌剂和素增敏剂作用。

Fructose was mainly used in metabolism in vivo,heat production,endogeny glucogenesis and insulin,platelet,microelement,and promoting cell caryocinesia or cytoprotection.

果糖主要用于体内代谢和产热、内源葡萄糖生成与素、血小板、体内微量元素及促进胞有丝分裂和胞保护。

It is suggested that lumbosacral agenesis, a severe congenital defect, might be one of the anomalies of diabetic embryopathy.

此病例显示腰荐椎发育不全可能是母亲糖尿病所导致胚胎病变的一种，且无论有无接受素治疗，此先天畸形仍可能形成。

So both cross-sectionally and prospectively researches have focused on the role of insulin resistance in the worsening of glucose tolerance.

因此，横断面研究和前瞻研究的研究焦点都在于素抵抗在糖耐量减低中的作用。

The key to treatment is to find and cope with shock, dehydration and hyperosmolality, especially to control blood sugar level with insulin.

救治的关键是及早发现并尽快抢救休克、脱、高渗状态，注意控制血糖是治疗关键，静滴素极其有效。

Moreover presence of insulin resistance and diabetes are risk factors for fibrosis progression and nonresponse to antiviral therapy in chronic hepatitis C (CHC).

此外，素抵抗和糖尿病是慢丙型肝炎（CHC）中纤维化进展以及对抗病毒治疗无应答的危险因素。

Conclusion: There is insulin resistance in patients with cerebral lacunal infarction.Cerebral insulin resistance may be one of its risk factors for cerebral lacunal infarction.

腔隙脑梗塞患者存在素抵抗，素抵抗可能是腔隙脑梗塞的危险因素之一。

Retinaldehyde (Rald), a metabolite of itamin A, increases the generation of adipose tissue and decreases insulin sensitiity, work conducted in a Harard Uniersity laboratory shows.

哈佛大学研究结果表明，维生素A的代谢产物视黄醛可以增加脂肪组织生成，降低素敏感。

Abstract: Objective To evaluate the clinical efficacy of dimethyldiguanide and Gliclazide capsule in treatment of type 2 diabetic insulin resistance (IR) and fat metabolism disorder.

目的观察比较二甲双胍与格列齐特对2型糖尿病素抵抗(IR)及脂代谢紊乱的疗效。

A report recently published in the American Journal of Epidemiology suggested that smoking increased the risk of developing non-insulin-dependent diabetes mellitus (NIDDM) by more than three times.

美国《流行病学杂志》最近发表的一份报告表明，吸烟使人们患非素依赖型糖尿病的危险增加了3倍多。

In conclusion, LBP possess the action of lowing blood glucose, improving morphogeny and function of pancreatic islet B cells and increasing the secretion of insulin in NIDDM mice.

枸杞多糖可以改善Ⅱ型糖尿病小鼠胞形态和功能并促进素的分泌，有良好的降血糖作用。

Our results provide evidence that small islets are superior to large islets with regard to in vitro insulin secretion and show a higher survival rate during both normoxic and hypoxic culture.

结果证明，不论是含氧量常还是在低氧培养条件下，小在体外素分泌方面由于大，并显示出相对较高的存活率。

However by 8 week IUGR rats developed hyper-insulinemia and high IRI.

胰岛素耐量实验显示IUGR子鼠对外源性胰岛素反应迟钝。

Therefore, an agent that has dual action (insulin secretagougue and sensitisation) is preferred for T2DM.

所以，有此双重作用（胰岛素促泌及增敏）的药物适用于T2DM。

In addition, there was breed difference of synergistic effect of glucose of insulin on lipogenesis.

同时，胰岛素和葡萄糖对脂肪生成的协同效应存在品种差异。

It has since been demonstrated that topiramate can act both as an insulin secretagogue and sensitiser in T2DM animal models.

这说明在T2DM动物模型中，同时有胰岛素促泌剂和胰岛素增敏剂作用。

Fructose was mainly used in metabolism in vivo,heat production,endogeny glucogenesis and insulin,platelet,microelement,and promoting cell caryocinesia or cytoprotection.

果糖主要用于体内代谢和产热、内源葡萄糖生成与胰岛素、血小板、体内微量元素及促进胞有丝分裂和胞保护。

It is suggested that lumbosacral agenesis, a severe congenital defect, might be one of the anomalies of diabetic embryopathy.

此病例显示腰荐椎发育不全可能是母亲糖尿病所导致胚胎病变的一种，且无论有无接受胰岛素治疗，此先仍可能成。

So both cross-sectionally and prospectively researches have focused on the role of insulin resistance in the worsening of glucose tolerance.

因此，横断面研究和前瞻性研究的研究焦点都在于胰岛素抵抗在糖耐量减低中的作用。

The key to treatment is to find and cope with shock, dehydration and hyperosmolality, especially to control blood sugar level with insulin.

救治的关键是及早发现并尽快抢救休克、纠正脱水、纠正高渗状态，注意控制血糖是治疗关键，静滴胰岛素极其有效。

Moreover presence of insulin resistance and diabetes are risk factors for fibrosis progression and nonresponse to antiviral therapy in chronic hepatitis C (CHC).

此外，胰岛素抵抗和糖尿病是慢性丙型肝炎（CHC）中纤维化进展以及对抗病毒治疗无应答的危险因素。

Conclusion: There is insulin resistance in patients with cerebral lacunal infarction.Cerebral insulin resistance may be one of its risk factors for cerebral lacunal infarction.

腔隙性脑梗塞患者存在胰岛素抵抗，胰岛素抵抗可能是腔隙性脑梗塞的危险因素之一。

Retinaldehyde (Rald), a metabolite of itamin A, increases the generation of adipose tissue and decreases insulin sensitiity, work conducted in a Harard Uniersity laboratory shows.

哈佛大学研究结果表明，维生素A的代谢产物视黄醛可以增加脂肪组织生成，降低胰岛素敏感性。

Abstract: Objective To evaluate the clinical efficacy of dimethyldiguanide and Gliclazide capsule in treatment of type 2 diabetic insulin resistance (IR) and fat metabolism disorder.

目的观察比较二甲双胍与格列齐特对2型糖尿病胰岛素抵抗(IR)及脂代谢紊乱的疗效。

A report recently published in the American Journal of Epidemiology suggested that smoking increased the risk of developing non-insulin-dependent diabetes mellitus (NIDDM) by more than three times.

美国《流行病学杂志》最近发表的一份报告表明，吸烟使人们患非胰岛素依赖型糖尿病的危险增加了3倍多。

In conclusion, LBP possess the action of lowing blood glucose, improving morphogeny and function of pancreatic islet B cells and increasing the secretion of insulin in NIDDM mice.

枸杞多糖可以改善Ⅱ型糖尿病小鼠胰岛胞态和功能并促进胰岛素的分泌，有良好的降血糖作用。

Our results provide evidence that small islets are superior to large islets with regard to in vitro insulin secretion and show a higher survival rate during both normoxic and hypoxic culture.

结果证明，不论是含氧量正常还是在低氧培养条件下，小胰岛在体外胰岛素分泌方面由于大胰岛，并显示出相对较高的存活率。

However by 8 week IUGR rats developed hyper-insulinemia and high IRI.

胰岛耐量实验显示IUGR子鼠对外源性胰岛迟钝。

Therefore, an agent that has dual action (insulin secretagougue and sensitisation) is preferred for T2DM.

所以，有此双重作用（胰岛促泌及增敏）的药物适用于T2DM。

In addition, there was breed difference of synergistic effect of glucose of insulin on lipogenesis.

同时，胰岛和葡萄糖对脂肪生成的协同效存在品种差异。

It has since been demonstrated that topiramate can act both as an insulin secretagogue and sensitiser in T2DM animal models.

这说明在T2DM动物模型中，托吡酯同时有胰岛促泌剂和胰岛增敏剂作用。

Fructose was mainly used in metabolism in vivo,heat production,endogeny glucogenesis and insulin,platelet,microelement,and promoting cell caryocinesia or cytoprotection.

果糖主要用于体内代谢和产热、内源葡萄糖生成与胰岛、血小板、体内微量元及促进胞有丝分裂和胞保护。

It is suggested that lumbosacral agenesis, a severe congenital defect, might be one of the anomalies of diabetic embryopathy.

此病例显示腰荐椎发育不全可能是母亲糖尿病所导致胚胎病变的一种，且无论有无接受胰岛治疗，此先天畸形仍可能形成。

So both cross-sectionally and prospectively researches have focused on the role of insulin resistance in the worsening of glucose tolerance.

因此，横断面研究和前瞻性研究的研究焦点都在于胰岛抵抗在糖耐量减低中的作用。

The key to treatment is to find and cope with shock, dehydration and hyperosmolality, especially to control blood sugar level with insulin.

救治的关键是及早发现并尽快抢救休克、水、高渗状态，注意控制血糖是治疗关键，静滴胰岛极其有效。

Moreover presence of insulin resistance and diabetes are risk factors for fibrosis progression and nonresponse to antiviral therapy in chronic hepatitis C (CHC).

此外，胰岛抵抗和糖尿病是慢性丙型肝炎（CHC）中纤维化进展以及对抗病毒治疗无答的危险因。

Conclusion: There is insulin resistance in patients with cerebral lacunal infarction.Cerebral insulin resistance may be one of its risk factors for cerebral lacunal infarction.

腔隙性脑梗塞患者存在胰岛抵抗，胰岛抵抗可能是腔隙性脑梗塞的危险因之一。

Retinaldehyde (Rald), a metabolite of itamin A, increases the generation of adipose tissue and decreases insulin sensitiity, work conducted in a Harard Uniersity laboratory shows.

哈佛大学研究结果表明，维生A的代谢产物视黄醛可以增加脂肪组织生成，降低胰岛敏感性。

Abstract: Objective To evaluate the clinical efficacy of dimethyldiguanide and Gliclazide capsule in treatment of type 2 diabetic insulin resistance (IR) and fat metabolism disorder.

目的观察比较二甲双胍与格列齐特对2型糖尿病胰岛抵抗(IR)及脂代谢紊乱的疗效。

A report recently published in the American Journal of Epidemiology suggested that smoking increased the risk of developing non-insulin-dependent diabetes mellitus (NIDDM) by more than three times.

美国《流行病学杂志》最近发表的一份报告表明，吸烟使人们患非胰岛依赖型糖尿病的危险增加了3倍多。

In conclusion, LBP possess the action of lowing blood glucose, improving morphogeny and function of pancreatic islet B cells and increasing the secretion of insulin in NIDDM mice.

枸杞多糖可以改善Ⅱ型糖尿病小鼠胰岛胞形态和功能并促进胰岛的分泌，有良好的降血糖作用。

Our results provide evidence that small islets are superior to large islets with regard to in vitro insulin secretion and show a higher survival rate during both normoxic and hypoxic culture.

结果证明，不论是含氧量常还是在低氧培养条件下，小胰岛在体外胰岛分泌方面由于大胰岛，并显示出相对较高的存活率。