With these medications around, aldosterone can't exert its effects.

有了这些药物，醛固酮就无法发挥其作用了。

Aldosterone is part of a hormone family or axis which work together and are called the renin-angiotensin-aldosterone system.

醛固酮属于一特激素家族激素轴的一部，这些激素共同作用，被称为素-血管紧张素-醛固酮系统。

An important hormone that helps regulate potassium reabsorption or secretion in the kidneys is aldosterone.

脏中一种帮助调节钾重吸泌的重要激素叫醛固酮。

Other pathological conditions that cause increased aldosterone levels include compensated heart failure and cirrhosis.

其他导致醛固酮水平增加的病理状包括代偿期心衰和肝硬化。

The diagnosis of hyperaldosteronism is mainly done by measuring levels of renin and aldosterone.

醛固酮增多症的诊断主要通过素与醛固酮的水平来完成。

Secondary causes of hyperaldosteronism are usually due to excess aldosterone production in response to high levels of renin.

醛固酮增多症的继发性原因通常是由于高水平素导致醛固酮生成过多。

When there is less sodium, the body increases activity in the renin-angiotensin-aldosterone system or the RAAS.

当体内钠含量较少时，人体 RAA 系统（素血管紧张素醛固酮系统）开始活跃。

Aldosterone has it's purpose, but it's not a hormone you want to regularly have high levels of.

醛固酮有其作用，但在人体中，这种荷尔蒙的水平不能太高。

Another example is a tumor that produces excess aldosterone, which just like renin, leads to fluid retention.

另一个例子是肿瘤的生长也会产生过多的醛固酮，一种类似于素的物质，会导致液体的积存。

Now, an important hormone that helps regulate potassium reabsorption or secretion in the kidneys is aldosterone.

所以，脏中有一种重要的激素可以帮助调节钾的重吸和泌，这就是醛固酮。

Hyperaldosteronism can also be due to secondary causes where the pathology lies outside of the adrenal gland.

醛固酮增多症也可以是继发性的，即病变位于上腺以外。

Hyperaldosteronism can happen due to primary causes which is where the adrenal gland itself is responsible for the excess production of aldosterone.

醛固酮增多症可以是原发性的，即上腺本身产生了过量的醛固酮。

So in this case aldosterone levels are high and renin levels are low in.

因此，在这种情下，醛固酮水平较高，素水平较低。

As this study shows, a low salt diet increases aldosterone by more than 3 fold in healthy people.

这项研究显示，健康正常人采用低盐饮食，其体内醛固酮水平将增加 3 倍有余。

This suggests that people actually following the WHO guidelines are chronically raising their aldosterone.

也就是说，遵循世卫组织关于盐摄入量建议的人们，他们体内的醛固酮长期处于较高水平。

This stimulates the release of aldosterone, which tries to bring blood pressure back up by telling the kidneys to retain more sodium and water.

这会刺激醛固酮的释放，醛固酮让脏保留更多的钠和水来尽量维持血压。

High aldosterone is associated with increased inflammation, Chronic kidney disease, Osteoporosis, and cardiovascular disease.

高醛固酮水平会增加体内炎症，导致慢性病、骨质疏松症以及心血管疾病。

In particular, it's implicated in oxidative stress and myocardial fibrosis — an abnormal thickening of the heart valves.

醛固酮与氧化应激和心肌纤维化（心脏瓣膜异常增厚）尤其相关。

On the flip side of aldosterone, there is a group of hormones called natriuretic hormones, i. e. sodium urinating hormones.

在醛固酮的另一面，有一组激素叫利钠激素，也就是钠尿荷尔蒙。

Less aldosterone floating around in the blood causes the body to start dumping sodium from the blood into the urine.

血中醛固酮减少使得尿钠排出增多。