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The conjugates of the present invention also exhibit an extended half-life in vivo compared to the corresponding unconjugated cytokine.

相对于未细胞因趋化因、生长因和多肽激素,本发明体内和体外显示出延长半衰期。

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Osmosis-尿

Chemokines attract neutrophils to the renal interstitium, but typically the glomeruli and vessels of the kidney are spared.

因子吸引中性粒细胞到达肾间质,但通常肾小球和肾血管不会受累。

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Osmosis-内分

Symptoms of neuroblastoma result from the chemokine release, and include fever, weight loss, sweating, and fatigue.

神经母细胞瘤症状的产生源于因子的释放,包括发热、体重减轻、出汗和乏力。

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Osmosis-内分

When any type of neuroblastoma forms, cells in the surrounding tissue release chemokines called CXCL12 and that stimulates nearby immune cells.

哪种神经母细胞瘤形成,周围组织的细胞都会释放CXCL12因子,激活附近的免疫细胞。

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Osmosis-微生物

Bacterial growth and death of alveolar macrophages produce powerful chemotactic factors that cause a large influx of polymorphonuclear leukocytes and monocytes from the peripheral blood.

军团菌的增长及肺细胞的死亡产生了强大的因子,造成大量多形核白细胞和单核细胞从外周血涌入。

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生物学基础入门

At the same time, the macrophages produce molecules called cytokines and chemokines that alert the rest of the immune system to the presence of the invader.

与此同时,细胞产生称为细胞因子和因子的分子,提醒免疫系统的其他部分注意入侵者的存在。

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双语版 TED-Ed 演讲精选

They initially circulate in the recipient's peripheral bloodstream, but molecules on the stem cells, called chemokines, act as homing devices and quickly traffic them back to the marrow.

这些细胞先在受者的外周血液中循环,不过干细胞上被称为 “因子” 的分子起到归巢作用,引导这些干细胞快速迁移回骨髓中。

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Osmosis-微生物

Immune cells release various chemokines which creates an inflammatory reaction that makes epithelial cells secrete more mucus and makes the blood vessels in the walls of the airways more leaky.

免疫细胞释放多种因子,产生炎症反应,使上皮细胞分更多黏液,并且使气管壁上的血管渗透性增加。

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Osmosis-神经

The immune system responds to the antigen by flooding the subarachnoid space with white blood cells, which, release chemokines - and create inflammation and this results in the classic triad of symptoms: headaches, fevers, and neck stiffness.

免疫系统检测到病原体之后,向蛛网膜下腔注入白细胞,以释放因子,造成炎症;这会导致经典的脑膜炎症状:头痛、发烧和颈部僵硬。

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