Those antibodies also activate the complement pathway which leads to muscle cell destruction.

这些体也会激活体通路，破坏肌肉细胞。

The complement system is a family of small proteins that work in an enzymatic cascade to fight off bacterial infections.

体系统是一群小的蛋白质，以酶促级联的方式抵细菌感染。

Rituximab is a monoclonal antibody that binds CD20 and induces complement-mediated lysis, as well as direct cytotoxicity and apoptosis.

利妥昔单是一种单克隆体，与CD20结合，诱导体介导的分解作用，以及直接的细胞毒性和凋亡。

Anti-Ro antibody Test 3) Complement (C3 and C5) level test, as their levels go down when lupus is more active.

Ro 体测试 3) 体（C3 和 C5）水平测试，因为当疮更加活跃时， 它们的水平会下降。

The activation of complement causes inflammation and destruction of the muscle cells and reduces the amount of acetylcholine receptors on the surface.

体激活引起炎症反应，破坏肌肉细胞，减少其表面的乙酰胆碱受体数量。

As the antibody- antigen complex circulates in the blood, the complex " fixes" complement to it.

结果是，体激活了强活性的酶的产生，穿透了细菌细胞壁，并使细菌有机体破裂。

Sometimes an antibody hooks to a bacterial antigen but needs an intermediate, or complement, to actually destroy the bacterium.

当体原复合物在血液循环中运行时，该结合体会与体结合。

Now, LPS has the ability to avoid complement-mediated killing by inhibiting the formation of the membrane attack complex and preventing membrane damage and bacterial cell death.

LPS可以通过抑制膜攻击复合物（MAC）的形成，逃避体介导的杀伤作用，防止细胞膜损伤和细菌死亡。

This happens when, in a phenomenon called autoimmunity, the body's own immune system attacks its complement of beta cells, wiping out as many as 80%.

这种现象称为自身免疫，即人体自身的免疫系统攻击其β细胞体，消灭多达 80% 的β细胞。

And on immunofluorescence, there might be nonspecific focal deposits of IgM and complement proteins, and these get trapped in the areas of hyalinosis, but these isn't always seen.

在免疫荧光电镜下，可能有非特异性病灶IgM和体蛋白沉积；这些沉积局限于玻璃样变区域，但不总是出现。

Other systems would usually help  - like the complement system, a sort of mobile minefield that can destroy viruses but  variola also manages to shut this down too.

其他系统通常会有所帮助——比如体系统，这是一种可以消灭病毒的移动雷区，但天花也能成功地关闭它。

When the abnormal IgA1-IgG immune complexes deposit in the mesangium, the alternative complement pathway is activated, leading to the release of proinflammatory cytokines and migration of macrophages into the kidney, all of which contributes to glomerular injury.

当异常的IgA1-IgG免疫复合物沉积在系膜上时，体旁路途径被激活，导致促炎因子的释放，同时促进巨噬细胞向肾迁移，以上所有反应会导致肾小球的损伤。