There is a space between a peribacteroid membrane and a bacteroid cell wall, the size of spaces is variable in different bacteroids or the different parts of a bacteroid.
Endothelial cell dysfunction causes vasoconstriction - narrowing of the blood vessels - and also affects the kidneys in a way that makes them retain more salt, both of which result in hypertension.
Now, if we look at a cross section of the lower leg, we can see that the fascia sends intermuscular septa that together with the interosseous membrane between the tibia and fibula divide the lower leg into four compartments