I've always wondered how does my sense of pain compare to other people's sense of pain.

我一直想知道我痛觉和别人痛觉相比如何。

Once activated, the trigeminal nerve transmits pain signals.

一旦被激活，三叉神经会传递痛觉信号。

During a migraine, this pain pathway becomes sensitized, meaning the threshold for provoking pain is lowered.

当偏头痛发作时，这个痛觉通路会变得敏感化，意思是能触发痛觉下降了。

Posture can even influence your emotional state and your sensitivity to pain.

姿势甚至可以影响你精神状态以及你对痛觉敏感度。

Damage to the spinothalamic tract causes a loss of temperature and pain sensation.

损伤脊髓丘脑束可以导致痛觉和温度觉丧。

Sense of touch and pain, do something totally different and it wasn't known how they do it.

触觉和痛觉作用是完全不同，我们不知道它们是如何作用。

And because your retinas don't have any pain receptors, your eyes have no way of warning you to stop.

而且因为你视网膜没有痛觉感受器，你眼睛无法警告你停下来。

The brain doesn't have pain receptors, so you can't feel the blockage itself.

大脑没有痛觉感受器，所以你感觉不到阻塞本身。

In a normal functioning human, motor response to pain is natural reflex.

对于正常人而言，对痛觉产生运动反射是一种自然反应。

Now, the harder you push against the needle, the closer you get to the nociceptor threshold.

但你越用力推针尖，越接近痛觉感受器。

When you eat something spicy, the pain receptors in your mouth initiate your body’s heat response.

当你吃辣东西时，你嘴里痛觉感受器会启动你身体热反应。

Without a scab to protect the exposed tissue, every little thing you do can stimulate pain receptors.

如果没有结痂来保护暴露组织，您所做每一件小事都会刺激痛觉感受器。

Certain chemicals can tune nociceptors, lowering their threshold for pain.

某些化学物质可以调节感受器，降低痛觉。

But the pain threshold isn't set in stone.

痛觉感受器并非一成不变。

But, unlike other nerve cells, nociceptors only fire if something happens that could cause or is causing damage.

不像其他神经细胞，痛觉感受器只在可能或正在造成伤害时才会作用。

By then, researchers had already discovered that immune cells called macrophages probably contribute to endometriosis and that pain-sensing nerves are also involved.

那时，研究人员已经发现， 被称为巨噬细胞免疫细胞可能与子宫内膜异位症有关， 痛觉神经也参与其中。

Push hard enough, and you'll cross that threshold and the nociceptors fire, telling your body to stop doing whatever you're doing.

很用力话，就会超过，痛觉感受器启动，告诉身体停止目前行为。

They showed that the drug interrupts the production of certain chemicals called prostaglandins, which control the transmission of pain sensations and inflammation.

他们表明，这种药物会中断某些称为前列腺素化学物质产生，这种化学物质控制痛觉和炎症传递。

This results in a loss of sensations like pain, temperature, touch, as well as paralysis or loss of muscle function in some parts of the body.

这会导致感觉丧（包括痛觉、温度觉、触觉）以及身体某些部位肌肉瘫痪或功能丧。

This ischemia is thought to trigger release of adenosine, bradykinin, and other molecules that stimulate nerve fibers in the myocardium that result in the sensation of pain.

心内膜下缺血被认为启动腺苷、缓激肽等分子释放，这些分子刺激心肌层神经末梢，导致痛觉产生。