Consequently RNA interference was observed is eukaryotic organisms including fungi, Arabidopsis,C. elegans, trypanosomes, hydra, planaria, Drosophila, zabrafish, and mouse.
The dorsoventral polarity of Drosophila egg is established by means of signaling between the germ line-derived oocyte and the surrounding somatic follicle cells.
Jarman, A. P., et al. "Atonal is a proneural gene that directs chordotonal organ formation in the Drosophila peripheral nervous system." Cell 73, 7 (1993): 1307-21.