At present, all over the world, about one hundred thousand uraemic patients, which is about 15 precent of the total dialysis population are accepting peritoneal dialysis treatment.
In contrast to simplistic expectations, the total amount of protofibrils and the amount of permeabilizing activity per mole protein in the protofibril fraction were reduced by the E46K mutation.
Among them East Asian element predominated over the other elements, making up 51.35 percent of the total species ,then Oriental element occupying 25.51%, Palaearctic 18.45% and Eurytopic only 2.26%.