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The expression of interleukin-5 (IL-5) has been correlated with the maturation and differentiation of eosinophils, and is considered to be a cytokine responsible for allergic inflammation.

IL-5与酸性粒细胞分化密切相关, 是过敏性炎症生过程中的关键细胞因子。

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This is the appearance of normal bone marrow smear at high magnification. Note the presence of an eosinophilic myelocyte, a basophilic myelocyte, and a plasma cell.

的正常骨髓涂片,可见一个酸性中幼粒细胞,一个碱性中幼粒细胞一个浆细胞。

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Osmosis-解剖与生理

Now, in comparison to neutrophils, eosinophils and basophils are far less common.

比起中性粒细胞酸性粒细胞碱性粒细胞要不常见得多。

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Osmosis-解剖与生理

Eosinophils stain pink with the dye eosin - which is where they get their name.

酸性粒细胞用伊红Eosin染色呈粉红色,也就是它英文名Eosinophil的来源。

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Osmosis-泌尿

This inflammation is caused by infiltration of immune cells, like neutrophils and eosinophils, which then cause inflammation.

这种炎症是由于免疫细胞渗入导致的,比如中性粒细胞酸性粒细胞,从炎症。

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Osmosis-解剖与生理

Unlike neutrophils and eosinophils, basophils are non-phagocytic.

和中性粒细胞酸性粒细胞不同的是,碱性粒细胞并不备吞噬功能。

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Osmosis-

The mucus may also contain Charcot-Leyden crystals which are shaped like needles and are formed by the breakdown of eosinophils.

黏液中也可能含有一些针状的Charcot-Leyden晶体,由酸性粒细胞分解形

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Osmosis-

IL-5, on the other hand, activates eosinophils which promote an immune response by releasing more cytokines and leukotrienes.

另一方面,IL-5激活酸性粒细胞,通过释放更多的细胞因子和白三烯来促进免疫反应。

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Osmosis-泌尿

Early symptoms include oliguria and eosinophiluria, which is eosinophils in the urine, but also general symptoms like a fever and a rash.

早期症状包括少尿和酸性尿,即尿液中存在酸性粒细胞,但也有发烧和皮疹等一般症状。

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Osmosis-心血管

Loffler syndrome, where eosinophils accumulate in the lung tissue, can also affect the heart tissue, called Loeffler endocarditis or sometimes loeffler endomyocarditis.

Loffler综合征:酸性粒细胞聚集在肺组织中,也可以累及心脏组织,这种情况叫做Loeffler心内膜炎,有时也叫Loeffler心内膜肌炎。

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豪斯医生一

That wouldn't give you an elevated eosinophil count.

脉管炎不会导致酸性粒细胞增加。

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Osmosis-解剖与生理

Eosinophils are also phagocytic, and they're best known for fighting large and unwieldy parasites because eosinophils are much larger than neutrophils and have receptors that are specific for parasites.

酸性粒细胞同样有吞噬作用,它们以对抗巨大笨重的寄生虫闻名,因为酸性粒细胞要比中性粒细胞大得多且有专门针对寄生虫的受体。

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经济学人-科技

The researchers could do this because they identified a distinctive antigen on the surface of the eosinophils: a receptor for the signalling molecule interleukin-5.

研究人员之所以能做到这一点,是因为他们发现了酸性粒细胞表面的一种独特抗原:信号分子白细胞介素5的受体。

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Osmosis-心血管

In this case, eosinophils accumulate in the endocardial layer of the heart tissue, causing inflammation and endocardial fibrosis, making it stiffer and again less compliant.

在这类病例中,酸性粒细胞聚集在心脏组织的心内膜层,导致炎症和心内膜纤维化,让其更加僵硬、顺应性更差。

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Osmosis-解剖与生理

They stain blue with the dye hematoxylin, and like eosinophils they can be helpful at combating large parasites but also cause inflammation in asthma and allergy responses.

它们用苏木素染色后呈蓝色;像酸性粒细胞一样,它们可以助力奋战寄生虫,但也会引起哮喘和过敏反应。

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2017级专外有声

Eosinophils take up a red acidic dye called eosin; their main function is to detoxify foreign proteins, especially those causing allergic reactions.

酸性粒细胞收一种叫做伊红的红色酸性染料;它们的主要功能是解除外源蛋白质,特别是那些引起过敏反应的蛋白质的毒性。

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2017级专外有声

There are five different types of leukocytes: three types of granulocytes (eosinophil, basophil, and neutrophil) and two types of agranulocytes (monocyte and lymphocyte).

三种粒细胞酸性粒细胞碱性粒细胞和中性粒细胞)和两种无粒细胞(单核细胞和淋巴细胞)。

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Osmosis-解剖与生理

Those cytokines start the inflammatory process by making blood vessels leaky and attracting nearby eosinophils, basophils, and mast cells, which release their own cytokines and granules amplifying the inflammation.

这些细胞因子将启动炎症过程:通过使血管渗漏并引附近的酸性粒细胞碱性粒细胞和肥大细胞;这些集结的细胞释放各自的细胞因子和颗粒,放大炎症反应。

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经济学人-科技

To design a therapy that could target eosinophils, the Chinese group, led by Peng Min at Tsinghua University in Beijing, added a CARprotein to the T-cell surface tailored to recognise this specific antigen.

为了设计一种可以针对酸性粒细胞的疗法,由清华大学彭敏领导的中国研究小组在T细胞表面添加了一种专门用于识别这种特定抗原的CAR蛋白。

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