Some congenital causes of primary hypogonadism are genetic diseases like Klinefelter or Turner syndrome.

可引起原发退的先天因包括Klinefelter综合征或Turner综合征等遗传病。

Next, endocrine dysfunctions that causes testosterone levels to fall, like hypogonadism, can cause erectile dysfunction.

其次，内分泌障碍导致睾酮水平下降，如退，会导致勃起障碍。

Some acquired causes of primary hypogonadism are radiation therapy, chemotherapy, and trauma to the gonads.

可引起原发退症的获得因有放疗、化疗和创伤。

These streak ovaries can't produce sex hormones, resulting in hypogonadism and low estrogen levels.

这些条索状卵巢无法产生激，导致低下、雌激水平低。

There are two main causes of hypogonadism.

退有两个主要病因。

Because of this, Kallmann syndrome is a type of hypogonadotropic hypogonadism disorder.

正因如此，Kallmann综合征是一种低促激退症。

Some acquired causes are similar to primary hypogonadism, radiation therapy, chemotherapy, and trauma to the gonads.

有些获得因与原发退症相似，也包括放疗、化疗和创伤。

Blood tests of hormone levels can give an idea of the type of hypogonadism.

血液激水平的检测可以为退的类型提供参考。

So, to recap: Kallmann syndrome is a type of hypogonadotropic hypogonadism where olfactory neurons and gonadotropin-releasing hormone neurons don't function normally.

Kallmann综合征是一种低促激退症，其嗅觉神经元与促激释放激神经元不发挥正常。

This leads to an overproduction of luteinizing and follicle stimulating hormones, so primary hypogonadism is also called hypergonadotropic hypogonadism.

这会导致LH和FSH生成过多，所以原发退症也称为高促激退症。

This is called hypergonadotropic (because the level of gonadotropins are high) hypogonadism (because the level of gonad or ovarian hormones is low).

由于促激水平高，而或卵巢激水平低，这被称为高促激型退症。

Though there are different causes which result in different levels of gonadotropin hormones, they all ultimately result in hypogonadism and a deficiency in testosterone or estrogen and progesterone.

尽管青春期延迟的病因很多，会导致促激水平各不相同，但最终的结果都是退以及男睾酮或女雌激和孕酮的缺乏。

The second cause of hypogonadism is secondary hypogonadism, which is also called hypogonadotropic hypogonadism because there are low levels of luteinizing and follicle stimulating hormones.

退的第二个病因是继发退症，也称为低促退症，因为LH和FSH激水平在此病中都显著降低。

Just like in secondary hypogonadism, there's a lack of gonadotropin-releasing hormone, but the key difference is that it's not considered pathologic - instead, it's thought to be a naturally slowed rate of maturation.

与继发退症类似，也存在GnRH的缺乏，但关键的区别在于这种缺乏不是病理的，而是一种正常的发育延迟。

Secondary hypogonadism can be due to hypothalamus or pituitary gland dysfunction; either from an inability to produce gonadotropin-releasing hormone or luteinizing and follicle stimulating hormones, or suppression from other hormones, like prolactin or thyroid hormone.

继发退症可由下丘脑或垂体障碍导致，既可是促激释放激、黄体生成和卵泡刺激的生成力低下，也可是以上激的分泌受到了其他激的抑制，例如泌乳或甲状激。

The first is primary hypogonadism which is caused by dysfunction of the gonads - for example, the gonad's receptors may not respond to gonadotropin hormones, or the gonads might not have healthy cells that are capable of producing hormone.

一是原发退，由障碍引起，例如，受体对促激不敏感或者内没有够产生激的健康细胞。