Objective: To evaluate the safety and efficacy of combining deferiprone(DFP)and deferoxamine(DFO)in iron chelation therapy in patients with thalassemia.
In this paper, the new chelating resin (PSIM) with a polythioether backbone bearing imidazole group is first synthesized by the reaction between polychloromethylthiirane and imidazole.
3, A chelating agent which forms an easily water-soluble metal chelated compound such as nitrilotriacetate (NTA) or ethylene diamine tetraacetate (EDTA) is incorporated in a detergent composition.
Another cytokine called IL-10 mediates the expression of increased ferritin receptors on the surface of macrophages, which then sequesters even more iron.
Finally, it needs iron to thrive and replicate, so it produces a siderophore, which is a term used for a group of small, high-affinity, iron chelating compounds that snatch iron from host cells.
剂去铁胺相比 ,瑞香素具有中度的铁
,
以取代传统
去铁胺(DFO)联
，
结合介质中
介素-10
介导巨噬细胞表面
体
