The other way epithelial cells can necrose is via nephrotoxins, which are substances that tend to damage the epithelial tubular cells.

另一种上皮细坏死的方于肾毒素，这些物质往往损坏肾小管上皮细。

Especially since rusty metal can create jagged wounds with lots of deoxygenated dead tissue for them to latch onto.

尤其生锈的金属会造成锯齿状伤口，带来大量脱氧的坏死细组织，伤口更易被附着（破伤风梭菌）。

In addition, dead cells and mucus slide into the airway forming mucus plugs which can trap air behind the plug.

此外，坏死的细和黏液滑气管形成黏液栓，并将空气堵在栓后。

After a while, they can begin to show signs of cellular damage and the epithelial cells can possibly even die off.

一段时间后，患者可能开始出现细损伤的症状，上皮细甚至可能相继坏死。

So my plan is to stand here for as many hours as it takes to scrape away every last cell of necrotic flesh.

我打算无论花多长时间，我都要站在这儿，将每一个坏死细干净。

For example you would expect to see an increase in transaminases, which are liver enzymes used for amino acid metabolism that get into the blood as liver cells die.

比如检测到转氨酶水平升高，它们肝细内酶，参与氨基酸代谢，在肝细坏死后进血液中。

Whatever the case, as the hepatocytes die and the liver becomes dysfunctional, blood doesn't get filtered, and so it doesn't get the nitrogen-containing toxins filtered by the liver like it normally would.

不论原因如何，随着肝细坏死，肝功失常，血液无法正常过滤，因而肝脏无法正常过滤含氮毒素。

Either way, this thing's gotta go, because all that inflammation and cell damage over time raises the risk of developing gallbladder cancer, so patients with porcelain gallbladder typically get it removed, called a cholecystectomy.

不管怎样，这种情况必须治疗，因为长期的炎症状态和细坏死将增加胆囊癌的发病风险，因此，瓷化胆囊的患者一般需行胆囊切术摘胆囊。