Later on, though, with extensive scarring, the liver progresses to decompensated cirrhosis, and can't function properly.

之后，随着大量瘢痕在脏内形成，硬化进展为失硬化，此时脏已无法正常工作。

The tissue that's encapsulated by the granuloma undergoes fibrosis and often calcification, producing scar tissue that can be seen on x-ray

被肉芽肿包裹的组织会纤维化且会钙化，形成瘢痕组织，这种钙化组织可以在X光片看到。

Alright, as a quick recap, cirrhosis is when inflammation and liver damage causes the liver to become fibrotic and develop scar tissue.

得！快速总结一下：硬化是指由炎症和脏损伤脏纤维化，并形成瘢痕组织。

Collagen builds up in the tissue around the eyes causing excessive fibrosis or scar tissue formation, this pushes on nerves, blood vessels, and the eye itself.

胶原在眼周组织堆积，度纤维化或瘢痕组织形成，进而压迫神经、血管和眼球本身。

During a flare, T-cells cause inflammation and damage to oligodendrocytes in the central nervous system, which leaves behind scarred areas of demyelinated neurons called plaques, which causes a variety of symptoms depending on the location.

在发作期间，T淋巴细胞炎症并损伤中枢神经系统的少突胶质细胞，在脱髓鞘神经元处形成瘢痕（硬化斑），从而根据部位的不同产生不同的症状。

When all that stuff stagnates, it initiates an inflammatory reaction that causes macrophages to release inflammatory molecules, which ultimately damage surrounding cells and leads to fibrosis which is the thickening of connective tissue, or the creation of scar tissue.

当所有这些物质淤滞时，将会引发炎症反应，从而巨噬细胞释放炎症因子，最终破坏周围细胞，造成组织的纤维化，即结缔组织增厚，形成瘢痕组织。