To detect the blood serum testosterone(T),pregnendione(P) and estradiol(E2)levels of the male patients with climacteric hypertension and the control group by radioimmunoassay.

用放免法测定男性更年期高血压病患及对照的血清酮(T)、孕酮(P)、雌二醇(E2)水平。

Methods 4 patients underwent testis homotransplantion with their relatives testis as donor tissue.Of them, 2 suffered from iatrogenic anorchia and the other 2 from hypogonadism.

方法利用亲属供体行同种异体移植4例,其中医源性无症2例,原性性腺机能低下2例,术后观察患血清酮水平、第二性征变化及性功能情况。

A mutant, TS-N-121 was obtained by mutation and plate screening from a parent strain Mycobacterium fortuitum MF2 , which could transform sterol into androstanedione as the main product.

从雄甾二酮的转化产生菌偶分枝杆菌MF2出,外诱变结合平板筛选,获得一株主要转化生产酮的突变株TS-N-121。

Conclusions Flutamide can cut down the secretory volume of T to block the sexual differentiation and development by the venenous harm on cellular organ and the restrained activity of key enzyme.

结论氟他胺通过对生成酮细胞器的毒性损害和关键酶的抑制，降低了酮的分泌量，从而阻碍了性分化和性育。

To detect the blood serum testosterone(T),pregnendione(P) and estradiol(E2)levels of the male patients with climacteric hypertension and the control group by radioimmunoassay.

用放免法测定男性更年期高血压病患及对照的血清睾酮(T)、孕酮(P)、雌二醇(E2)。

Methods 4 patients underwent testis homotransplantion with their relatives testis as donor tissue.Of them, 2 suffered from iatrogenic anorchia and the other 2 from hypogonadism.

方法利用亲属睾丸作供体行同种异体睾丸移植4,其中医源性无睾症2,原发性性腺机能低2,后观察患血清睾酮、二性征变化及性功能情况。

A mutant, TS-N-121 was obtained by mutation and plate screening from a parent strain Mycobacterium fortuitum MF2 , which could transform sterol into androstanedione as the main product.

从雄甾二酮的转化产生菌偶发分枝杆菌MF2出发,经紫外诱变结合板筛选,获得一株主要转化生产睾酮的突变株TS-N-121。

Conclusions Flutamide can cut down the secretory volume of T to block the sexual differentiation and development by the venenous harm on cellular organ and the restrained activity of key enzyme.

结论氟他胺通过对生成睾酮细胞器的毒性损害和关键酶的抑制，降低了睾酮的分泌量，从而阻碍了性分化和性发育。

To detect the blood serum testosterone(T),pregnendione(P) and estradiol(E2)levels of the male patients with climacteric hypertension and the control group by radioimmunoassay.

用放免法测定男性更年期高血压病患及对照血清睾酮(T)、孕酮(P)、雌二醇(E2)水平。

Methods 4 patients underwent testis homotransplantion with their relatives testis as donor tissue.Of them, 2 suffered from iatrogenic anorchia and the other 2 from hypogonadism.

方法利用亲属睾丸作供体行同种异体睾丸移植4例,其中医源性无睾症2例,原发性性腺机能低下2例,术后观察患血清睾酮水平、第二性征变化及性功能情况。

A mutant, TS-N-121 was obtained by mutation and plate screening from a parent strain Mycobacterium fortuitum MF2 , which could transform sterol into androstanedione as the main product.

从雄甾二酮转化产生菌偶发分枝杆菌MF2出发,经紫外诱变结合平板筛选,获得一株主要转化生产睾酮突变株TS-N-121。

Conclusions Flutamide can cut down the secretory volume of T to block the sexual differentiation and development by the venenous harm on cellular organ and the restrained activity of key enzyme.

结论氟他胺通过对生成睾酮细胞器毒性损害和关键制，降低了睾酮分泌量，从而阻碍了性分化和性发育。

To detect the blood serum testosterone(T),pregnendione(P) and estradiol(E2)levels of the male patients with climacteric hypertension and the control group by radioimmunoassay.

用放免法测定男性更年期高血压病患及对照的血清睾酮(T)、孕酮(P)、雌二醇(E2)水平。

Methods 4 patients underwent testis homotransplantion with their relatives testis as donor tissue.Of them, 2 suffered from iatrogenic anorchia and the other 2 from hypogonadism.

方法利用亲属睾体行同种异体睾移植4例,其中医源性无睾症2例,原性性腺机能低下2例,术后观察患血清睾酮水平、第二性征变化及性功能情况。

A mutant, TS-N-121 was obtained by mutation and plate screening from a parent strain Mycobacterium fortuitum MF2 , which could transform sterol into androstanedione as the main product.

从雄甾二酮的转化产生菌偶分枝杆菌MF2,紫外诱变结合平板筛选,获得一株主要转化生产睾酮的突变株TS-N-121。

Conclusions Flutamide can cut down the secretory volume of T to block the sexual differentiation and development by the venenous harm on cellular organ and the restrained activity of key enzyme.

结论氟他胺通过对生成睾酮细胞器的毒性损害和关键酶的抑制，降低了睾酮的分泌量，从而阻碍了性分化和性育。

To detect the blood serum testosterone(T),pregnendione(P) and estradiol(E2)levels of the male patients with climacteric hypertension and the control group by radioimmunoassay.

用放免法测定男性更年期高压病及对照的睾酮(T)、孕酮(P)、雌二醇(E2)水平。

Methods 4 patients underwent testis homotransplantion with their relatives testis as donor tissue.Of them, 2 suffered from iatrogenic anorchia and the other 2 from hypogonadism.

方法利用亲属睾丸作供体行同种异体睾丸移植4例,其中医源性无睾症2例,原发性性腺机能低下2例,术后观睾酮水平、第二性征变化及性功能情况。

A mutant, TS-N-121 was obtained by mutation and plate screening from a parent strain Mycobacterium fortuitum MF2 , which could transform sterol into androstanedione as the main product.

从雄甾二酮的转化产生菌偶发分枝杆菌MF2出发,经紫外诱变结合平板筛选,获得一株主要转化生产睾酮的突变株TS-N-121。

Conclusions Flutamide can cut down the secretory volume of T to block the sexual differentiation and development by the venenous harm on cellular organ and the restrained activity of key enzyme.

结论氟他胺通过对生成睾酮细胞器的毒性损害和关键酶的抑制，降低了睾酮的分泌量，从而阻碍了性分化和性发育。

To detect the blood serum testosterone(T),pregnendione(P) and estradiol(E2)levels of the male patients with climacteric hypertension and the control group by radioimmunoassay.

用放免法测定男性更年期高血压病患及对照的血清酮(T)、孕酮(P)、雌二醇(E2)水平。

Methods 4 patients underwent testis homotransplantion with their relatives testis as donor tissue.Of them, 2 suffered from iatrogenic anorchia and the other 2 from hypogonadism.

方法利用亲属作供体行同种异体植4例,其中医源性无症2例,原发性性腺机能低下2例,术后观察患血清酮水平、第二性征变化及性功能情况。

A mutant, TS-N-121 was obtained by mutation and plate screening from a parent strain Mycobacterium fortuitum MF2 , which could transform sterol into androstanedione as the main product.

从雄甾二酮的转化偶发分枝杆MF2出发,经紫外诱变结合平板筛选,获得一株主要转化酮的突变株TS-N-121。

Conclusions Flutamide can cut down the secretory volume of T to block the sexual differentiation and development by the venenous harm on cellular organ and the restrained activity of key enzyme.

结论氟他胺通过对成酮细胞器的毒性损害和关键酶的抑制，降低了酮的分泌量，从而阻碍了性分化和性发育。

To detect the blood serum testosterone(T),pregnendione(P) and estradiol(E2)levels of the male patients with climacteric hypertension and the control group by radioimmunoassay.

用放免法测定男性更年期高血压及对照的血清睾酮(T)、孕酮(P)、雌二醇(E2)水平。

Methods 4 patients underwent testis homotransplantion with their relatives testis as donor tissue.Of them, 2 suffered from iatrogenic anorchia and the other 2 from hypogonadism.

方法利用亲属睾丸作供体行同种异体睾丸移植4例,其中医源性无睾症2例,原发性性腺机能低下2例,术后观察血清睾酮水平、第二性征化及性功能情况。

A mutant, TS-N-121 was obtained by mutation and plate screening from a parent strain Mycobacterium fortuitum MF2 , which could transform sterol into androstanedione as the main product.

从雄甾二酮的转化产生菌偶发分枝杆菌MF2出发,经紫外诱结合平板筛选,获得一主要转化生产睾酮的TS-N-121。

Conclusions Flutamide can cut down the secretory volume of T to block the sexual differentiation and development by the venenous harm on cellular organ and the restrained activity of key enzyme.

结论氟他胺通过对生成睾酮细胞器的毒性损害和关键酶的抑制，降低了睾酮的分泌量，从而阻碍了性分化和性发育。

To detect the blood serum testosterone(T),pregnendione(P) and estradiol(E2)levels of the male patients with climacteric hypertension and the control group by radioimmunoassay.

用放免法测定男性更年期高血压病患及对照血清睾酮(T)、孕酮(P)、雌二醇(E2)水平。

Methods 4 patients underwent testis homotransplantion with their relatives testis as donor tissue.Of them, 2 suffered from iatrogenic anorchia and the other 2 from hypogonadism.

方法利用亲属睾丸作供体行同种异体睾丸移植4例,其中医源性无睾症2例,原发性性腺机能低下2例,术后观察患血清睾酮水平、第二性征变化及性功能情况。

A mutant, TS-N-121 was obtained by mutation and plate screening from a parent strain Mycobacterium fortuitum MF2 , which could transform sterol into androstanedione as the main product.

从雄甾二酮转化产生菌偶发分枝杆菌MF2出发,经紫外诱变结合平板筛选,获得一株主要转化生产睾酮突变株TS-N-121。

Conclusions Flutamide can cut down the secretory volume of T to block the sexual differentiation and development by the venenous harm on cellular organ and the restrained activity of key enzyme.

结论氟他胺通过对生成睾酮细胞器毒性损害和关键制，降低了睾酮分泌量，从而阻碍了性分化和性发育。

To detect the blood serum testosterone(T),pregnendione(P) and estradiol(E2)levels of the male patients with climacteric hypertension and the control group by radioimmunoassay.

用放免法测定男性更年期高血压病患及对照的血(T)、孕(P)、雌二醇(E2)水平。

Methods 4 patients underwent testis homotransplantion with their relatives testis as donor tissue.Of them, 2 suffered from iatrogenic anorchia and the other 2 from hypogonadism.

方法利用亲属丸作供体行同种异体丸移植4例,其中医源性无症2例,原发性性腺机能低下2例,术患血水平、第二性征变化及性功能情况。

A mutant, TS-N-121 was obtained by mutation and plate screening from a parent strain Mycobacterium fortuitum MF2 , which could transform sterol into androstanedione as the main product.

从雄甾二的转化产生菌偶发分枝杆菌MF2出发,经紫外诱变结合平板筛选,获得一株主要转化生产的突变株TS-N-121。

Conclusions Flutamide can cut down the secretory volume of T to block the sexual differentiation and development by the venenous harm on cellular organ and the restrained activity of key enzyme.

结论氟他胺通过对生成细胞器的毒性损害和关键酶的抑制，降低了的分泌量，从而阻碍了性分化和性发育。