Ankylosing spondylitis, also called Bechterew disease, is part of a group of diseases called seronegative spondyloarthropathies.

脊柱炎也称Bechterew，是一类旧称为“血清阴脊柱”的疾中的一种。

In ankylosing spondylitis there's chronic inflammation of the intervertebral joints and the facet joints of the spine.

患有脊柱炎时，椎间盘和突内存在炎症。

Inflammation and pain from ankylosing spondylitis is usually treated with non-steroidal anti-inflammatory drugs like ibuprofen.

脊柱炎的炎症和疼痛通常采用如布洛芬等非甾体类抗炎药来治疗。

Ankylosing spondylitis is a systemic inflammatory disease, so it can cause symptoms, like weight loss, fevers, and fatigue.

脊柱炎是一种全身的炎症疾，因此能够引起全身症状，如体重减轻、发热和疲劳。

Ankylosing spondylitis can be diagnosed using MRI, where there's typically erosion and narrowing of the joint spaces early on, and joint fusion later on.

利用MRI可诊断脊柱炎，程早期通常可见腔的侵蚀和狭窄，晚期可见融合。

Most individuals with ankylosing spondylitis have the gene HLA-B27, which is a gene that encodes for a specific type of MHC class I molecule.

许多脊柱炎患者都携带HLA-B27基因，该基因能编码一种特定的MHC Ⅰ类分子。

So ankylosing spondylitis is a chronic inflammatory disease that affects the vertebral joints and makes the spine really stiff, but can also cause inflammation in other parts of the body like the eyes and blood vessels.

因此，脊柱炎是一种累及脊柱并使脊柱变得僵的慢炎症疾；它也会累及身体其他部位，如眼部和血管。